Scroll News
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
Scroll News
No Result
View All Result
Home Lifestyle Health & Fitness

Cord Blood transplant outperforms bone marrow transplant states a new study by ASH

Scroll News by Scroll News
March 31, 2021
in Health & Fitness
0
Share on FacebookShare on Twitter
  • Published in the journal – Blood Advances – the studies aim to study the efficacy of cord blood in treatment of diverse disorders

  • Studies’ outcome crucial for multi-ethnic country like India, where the chances of finding a matching donor are very low.

New Delhi: American Society of Hematology (ASH), the world’s largest professional society working to conquer blood diseases has recently released two key studies on cord blood transplants, as part of its Blood Advances journal. Led by a team of leading researchers from University of Colorado and University of Pittsburgh, the two studies have brought to foray the various benefits of cord blood transplant over bone marrow in cancerous and non-cancerous disorders. With the growing concerns among medical fraternity about finding matching bone marrow donors in a multi-ethnic country like India, the findings of the studies clearly outline the efficacy of cord blood in the treatment of diverse disorders.

In the study conducted to weigh benefits of cord blood transplant over bone marrow transplant for cancerous disorders, University of Colorado researchers compared the outcomes of matched bone marrow and double-unit cord blood transplants in adults. Amongst the 313 patients studied (190 cord blood transplant and 123 matched related donor transplant patients), the two key findings emerged. One, Chances of developing graft versus host disease were higher with bone marrow as compared to cord blood transplants and two, it was discovered that relapse rates were lower in patients who received a cord blood transplant.

You May Also Like This

India’s Dengue Hotspots: PharmEasy Report Shows Karnataka, Tamil Nadu, and Maharashtra Leading the Charts

India’s Dengue Hotspots: PharmEasy Report Shows Karnataka, Tamil Nadu, and Maharashtra Leading the Charts

August 29, 2025
Redefining Fitness In India: Siraj Lalani’s Vision With Plus Fitness 

Redefining Fitness In India: Siraj Lalani’s Vision With Plus Fitness 

August 13, 2025
Robotic-Assisted Breast Surgery: A New Era in Cancer Care- Dr. Sandeep Nayak

Robotic-Assisted Breast Surgery: A New Era in Cancer Care- Dr. Sandeep Nayak

July 31, 2025

Followed by the findings of the first study, a second study on the efficacy of cord blood transplant among non-cancerous disorders was also undertaken by a team of researchers from University of Pittsburgh. The researchers successfully treated 44 children suffering from various non-cancerous & immune disorders with a combination of low dose chemotherapy and single-unit of HLA-mismatched cord blood with no cell expansion. The successful outcomes provided by this first of its kind and the largest trial showed that cord blood outperformed bone marrow in terms of graft failure, treatment related mortality and event-free survival. Also, this gives tremendous confidence to patients & doctors in a multi-ethnic country like India where the chances of finding a matching donor are very low.

Commenting on this, Dr. Sunil Bhat, MBBS, MD (Pediatrics) Mazumdar Shaw Cancer Centre, Narayana Health City, Bengaluru said, “Authors have tried a new conditioning regimen which is “reduced toxicity” hence less toxic to the patients but at the same time quite effective resulting into good outcomes in these difficult disease conditions. The application of “immune boost” post-transplant is also novel and results into better immune recovery and less complications especially of infections post cord blood transplant.”

“Another study which was published during same year gives a clear understanding on how to select a cord blood donor based on Human Leukocyte Antigens (HLA) match and also makes clear recommendations on the stem cell dose required for successful transplant. This study is also a great guide to the physicians to select cord blood donors for transplant purpose.

Other key highlights from the studies:

Study 1 – To understand the efficacy of Cord Blood transplants over bone marrow for Cancerous disorders

  • Outcomes of this study demonstrated that cancer patients undergoing cord blood transplants showed better improvement & developed lesser complications than those who received matched sibling donor transplants.
  • The overall improved recovery rate and lack of complications resulted in low costs associated with post-transplant care.
  • This treatment protocol had a distinct positive impact on the patients’ quality of life.

 

Study 2 – To understand the efficacy of Cord Blood transplants over bone marrow for non-cancerous disorders

  • The graft failure rate of <5% seen in this trial is the lowest ever reported for non-manipulated cord blood grafts in non-cancerous or even in cancerous diseases.
  • The lowest 1-year (Treatment-Related Mortality) TRM of 5%, resulting in >90% Event Free Survival (EFS) at 1 year was reported.
  • A single unit of allogeneic cord blood could be identified for each of the 44 eligible children regardless of their ethnicities, showing the unique and unparalleled suitability of cord blood grafts even without being perfectly (HLA) matched.
  • No cell expansion was required in the trial. In general, a single cord blood unit doesn’t have sufficient stem cells to treat adults.
  • No patient developed severe chronic graft versus host disease and a distinct improvement in the quality of life was reported.
  • The novel treatment protocol used in the trial prevented graft failure and aided immune reconstitution.
ShareTweetShareShareSendSend
Previous Post

A women-led startup develops deep-tech for reliable low-cost internet services to rural areas

Next Post

New hope for mitochondrial disorders

Related Posts

India’s Dengue Hotspots: PharmEasy Report Shows Karnataka, Tamil Nadu, and Maharashtra Leading the Charts
Health & Fitness

India’s Dengue Hotspots: PharmEasy Report Shows Karnataka, Tamil Nadu, and Maharashtra Leading the Charts

August 29, 2025
Redefining Fitness In India: Siraj Lalani’s Vision With Plus Fitness 
Health & Fitness

Redefining Fitness In India: Siraj Lalani’s Vision With Plus Fitness 

August 13, 2025
Robotic-Assisted Breast Surgery: A New Era in Cancer Care- Dr. Sandeep Nayak
Health & Fitness

Robotic-Assisted Breast Surgery: A New Era in Cancer Care- Dr. Sandeep Nayak

July 31, 2025
The Science of Thicker Hair: Why Combining Bio-FUE with GFC Is Redefining Hair Restoration
Health & Fitness

The Science of Thicker Hair: Why Combining Bio-FUE with GFC Is Redefining Hair Restoration

July 24, 2025
Breathe Easy This Monsoon: Pravek Kalp’s Ayurvedic ‘Cough Kalp’ Offers Natural Relief
Health & Fitness

Breathe Easy This Monsoon: Pravek Kalp’s Ayurvedic ‘Cough Kalp’ Offers Natural Relief

July 23, 2025
India’s First Clean Supplement Brand to Put a Traffic Light on ‘Healthy’ Food
Health & Fitness

India’s First Clean Supplement Brand to Put a Traffic Light on ‘Healthy’ Food

July 18, 2025
Next Post

New hope for mitochondrial disorders

Salt substitution is effective to reduce blood pressure in rural India

Meet Mr. Chandresh Pandey and his life as a Fashion Influencer

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recommended

Social media giant Facebook backs Aryan Saha for his mental health initiative

Social media giant Facebook backs Aryan Saha for his mental health initiative

2 years ago

DeSpace Protocol collaborating with Nyrraa M Banerji and Nishant Malkhani to launch their NFT drops

4 years ago
Pave the way for MOTION: A new era in Health and Wellness

Pave the way for MOTION: A new era in Health and Wellness

3 years ago
A Trade Wake-Up Call: How U.S. Tariffs Are Shaking Indian Markets and Why Zebu Is the Investor’s Anchor

A Trade Wake-Up Call: How U.S. Tariffs Are Shaking Indian Markets and Why Zebu Is the Investor’s Anchor

5 months ago

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Gadgets
  • Health & Fitness
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • World

Topics

Ace Entrepreneur actor Artificial intelligence Bangalore Bengaluru Blockchain technology BRICS CCI Content Creator COVID-19 Cryptocurrency CSIR DBT Delhi Digital Marketing digital marketing agency DST Dubai Education entrepreneur entrepreneurship Fairplay Gujarat Gurugram Hyderabad IIT Delhi India Indian Institute of Technology Influencer Influencerquipo innovation Kingston Technology K Raheja Corp Homes memory products and technology solutions Mumbai Music Industry pandemic photography producer Pune real estate research Shan Se Entertainment Shantanu Bhamare social media Surat
No Result
View All Result

Highlights

Onlive Server Rolls Out Premium 10 Gbps France Dedicated Server Plans with No Setup Fees

Over 500 Participate in Wheelchair Sports & Cultural Program & Inclusive Health Checkup camp at NCDC for Spinal Cord Injury Day & National Injury Prevention Week 2025

JD Institute of Fashion Technology and JD School of Design Launch Future-Ready Digital Design Experience Programs in Bengaluru

India’s Dengue Hotspots: PharmEasy Report Shows Karnataka, Tamil Nadu, and Maharashtra Leading the Charts

Visionnaire introduces its Neolito Bedroom

Stop Collecting, Start Connecting: Helo.ai’s Prashant Gadekar Unveils Future of CX at IAMAI CLICK Summit

Trending

Breaking the Monotony: How NoMoreType is Redefining Digital Lifestyle Shopping
Lifestyle

Breaking the Monotony: How NoMoreType is Redefining Digital Lifestyle Shopping

by Scroll News
September 8, 2025
0

The global lifestyle e-commerce market, valued at $368 billion in 2024, faces a curious problem. Despite endless...

From Flood Ruins to Global Recognition: Vilvex Cables’ Remarkable CE Marking Achievement

From Flood Ruins to Global Recognition: Vilvex Cables’ Remarkable CE Marking Achievement

September 5, 2025
India’s First Nanobubble Pioneer: How Prasinos Made World-Class Technology Affordable for Everyone

India’s First Nanobubble Pioneer: How Prasinos Made World-Class Technology Affordable for Everyone

September 5, 2025
Onlive Server Rolls Out Premium 10 Gbps France Dedicated Server Plans with No Setup Fees

Onlive Server Rolls Out Premium 10 Gbps France Dedicated Server Plans with No Setup Fees

September 5, 2025
Over 500 Participate in Wheelchair Sports & Cultural Program & Inclusive Health Checkup camp at NCDC for Spinal Cord Injury Day & National Injury Prevention Week 2025

Over 500 Participate in Wheelchair Sports & Cultural Program & Inclusive Health Checkup camp at NCDC for Spinal Cord Injury Day & National Injury Prevention Week 2025

September 1, 2025
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2022 Scroll News

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 Scroll News