Scroll News
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
Scroll News
No Result
View All Result
Home Lifestyle Health & Fitness

Cord Blood transplant outperforms bone marrow transplant states a new study by ASH

Scroll News by Scroll News
March 31, 2021
in Health & Fitness
0
Share on FacebookShare on Twitter
  • Published in the journal – Blood Advances – the studies aim to study the efficacy of cord blood in treatment of diverse disorders

  • Studies’ outcome crucial for multi-ethnic country like India, where the chances of finding a matching donor are very low.

New Delhi: American Society of Hematology (ASH), the world’s largest professional society working to conquer blood diseases has recently released two key studies on cord blood transplants, as part of its Blood Advances journal. Led by a team of leading researchers from University of Colorado and University of Pittsburgh, the two studies have brought to foray the various benefits of cord blood transplant over bone marrow in cancerous and non-cancerous disorders. With the growing concerns among medical fraternity about finding matching bone marrow donors in a multi-ethnic country like India, the findings of the studies clearly outline the efficacy of cord blood in the treatment of diverse disorders.

In the study conducted to weigh benefits of cord blood transplant over bone marrow transplant for cancerous disorders, University of Colorado researchers compared the outcomes of matched bone marrow and double-unit cord blood transplants in adults. Amongst the 313 patients studied (190 cord blood transplant and 123 matched related donor transplant patients), the two key findings emerged. One, Chances of developing graft versus host disease were higher with bone marrow as compared to cord blood transplants and two, it was discovered that relapse rates were lower in patients who received a cord blood transplant.

You May Also Like This

The NeuroAid and Research Foundation supported by Apollo Hospitals is organising a Music therapy Event

The NeuroAid and Research Foundation supported by Apollo Hospitals is organising a Music therapy Event

June 9, 2023
Narayana Health welcomes Internationally Acclaimed Orthopedic, Spine and Trauma Expert, Professor (Dr) Arun Ranganathan

Narayana Health welcomes Internationally Acclaimed Orthopedic, Spine and Trauma Expert, Professor (Dr) Arun Ranganathan

May 18, 2023
SAKRA World Hospital launches the SAKRA Information Centre in Bardhaman, West Bengal

SAKRA World Hospital launches the SAKRA Information Centre in Bardhaman, West Bengal

May 9, 2023

Followed by the findings of the first study, a second study on the efficacy of cord blood transplant among non-cancerous disorders was also undertaken by a team of researchers from University of Pittsburgh. The researchers successfully treated 44 children suffering from various non-cancerous & immune disorders with a combination of low dose chemotherapy and single-unit of HLA-mismatched cord blood with no cell expansion. The successful outcomes provided by this first of its kind and the largest trial showed that cord blood outperformed bone marrow in terms of graft failure, treatment related mortality and event-free survival. Also, this gives tremendous confidence to patients & doctors in a multi-ethnic country like India where the chances of finding a matching donor are very low.

Commenting on this, Dr. Sunil Bhat, MBBS, MD (Pediatrics) Mazumdar Shaw Cancer Centre, Narayana Health City, Bengaluru said, “Authors have tried a new conditioning regimen which is “reduced toxicity” hence less toxic to the patients but at the same time quite effective resulting into good outcomes in these difficult disease conditions. The application of “immune boost” post-transplant is also novel and results into better immune recovery and less complications especially of infections post cord blood transplant.”

“Another study which was published during same year gives a clear understanding on how to select a cord blood donor based on Human Leukocyte Antigens (HLA) match and also makes clear recommendations on the stem cell dose required for successful transplant. This study is also a great guide to the physicians to select cord blood donors for transplant purpose.

Other key highlights from the studies:

Study 1 – To understand the efficacy of Cord Blood transplants over bone marrow for Cancerous disorders

  • Outcomes of this study demonstrated that cancer patients undergoing cord blood transplants showed better improvement & developed lesser complications than those who received matched sibling donor transplants.
  • The overall improved recovery rate and lack of complications resulted in low costs associated with post-transplant care.
  • This treatment protocol had a distinct positive impact on the patients’ quality of life.

 

Study 2 – To understand the efficacy of Cord Blood transplants over bone marrow for non-cancerous disorders

  • The graft failure rate of <5% seen in this trial is the lowest ever reported for non-manipulated cord blood grafts in non-cancerous or even in cancerous diseases.
  • The lowest 1-year (Treatment-Related Mortality) TRM of 5%, resulting in >90% Event Free Survival (EFS) at 1 year was reported.
  • A single unit of allogeneic cord blood could be identified for each of the 44 eligible children regardless of their ethnicities, showing the unique and unparalleled suitability of cord blood grafts even without being perfectly (HLA) matched.
  • No cell expansion was required in the trial. In general, a single cord blood unit doesn’t have sufficient stem cells to treat adults.
  • No patient developed severe chronic graft versus host disease and a distinct improvement in the quality of life was reported.
  • The novel treatment protocol used in the trial prevented graft failure and aided immune reconstitution.
ShareTweetShareShareSendSend
Previous Post

A women-led startup develops deep-tech for reliable low-cost internet services to rural areas

Next Post

New hope for mitochondrial disorders

Related Posts

The NeuroAid and Research Foundation supported by Apollo Hospitals is organising a Music therapy Event
Health & Fitness

The NeuroAid and Research Foundation supported by Apollo Hospitals is organising a Music therapy Event

June 9, 2023
Narayana Health welcomes Internationally Acclaimed Orthopedic, Spine and Trauma Expert, Professor (Dr) Arun Ranganathan
Health & Fitness

Narayana Health welcomes Internationally Acclaimed Orthopedic, Spine and Trauma Expert, Professor (Dr) Arun Ranganathan

May 18, 2023
SAKRA World Hospital launches the SAKRA Information Centre in Bardhaman, West Bengal
Health & Fitness

SAKRA World Hospital launches the SAKRA Information Centre in Bardhaman, West Bengal

May 9, 2023
Sharp Sight goes above and beyond for employees with ESOP offering
Health & Fitness

Sharp Sight goes above and beyond for employees with ESOP offering

April 25, 2023
P&G Health collaborates with the Indian Medical Association, launches VitaM.I.N.D.S conclave
Health & Fitness

P&G Health collaborates with the Indian Medical Association, launches VitaM.I.N.D.S conclave

April 18, 2023
Polybion celebrates World Health Day, launches ‘Pragati Utsav’ to raise awareness on Vitamin B Deficiency
Health & Fitness

Polybion celebrates World Health Day, launches ‘Pragati Utsav’ to raise awareness on Vitamin B Deficiency

April 7, 2023
Next Post

New hope for mitochondrial disorders

Salt substitution is effective to reduce blood pressure in rural India

Meet Mr. Chandresh Pandey and his life as a Fashion Influencer

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recommended

Dr. Harsh Vardhan felicitates Kayakalp award to Public and Private Health Facilities for high standards of Sanitation and Hygiene

2 years ago

Presidential Train Now Available For Jakartans Traveling To Bandung

1 year ago

Hong Kong based Indian Designer Manish Talwar brings you his new wedding collection

1 year ago

Gadkari Announces Enforcement of Mandatory FASTag from 1st January, 2020

2 years ago

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Gadgets
  • Health & Fitness
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • World

Topics

Ace Entrepreneur Ahmedabad Artificial intelligence Bengaluru Blockchain technology Content Creator COVID-19 CSIR DBT Delhi Department of Biotechnology DeSpace Protocol Digital Marketing disease DST Dubai Education entrepreneur environment Fairplay Gujarat health Hyderabad IIT Delhi Indian Institute of Technology Influencer Influencerquipo innovation Kingston Technology K Raheja Corp Homes MoES Mumbai Music Industry NFT pandemic photography Pune R&D real estate research science social media Surat technology TTK Prestige
No Result
View All Result

Highlights

Dr Vinod K Verma was Honored with Economic Times Inspiring Leaders Award 2023 for Remarkable Policy Advocacy Contributions

Exciting times for Billiards & Snooker, as IOA authorizes participation of BSFI in the National Games: Rajan Khinvasara

Phoenix Business Advisory welcomes Bollywood Icon Nargis Fakhri as Brand Ambassador to elevate Global Recognition

Revolutionary Guru Paramahamsa Vishwananda to Inaugurate Sri Vittal Dham Mandir in Germany

FairPlay Continues Betting Excitement with Live Casinos and Live Card Games

Doceree Is Now Great Place To Work Certified

Trending

FairPlay Offers Unbeatable Benefits for Betting Enthusiasts with Fantasy Pro
Press Release

With Fantasy Pro, FairPlay Provides Unbeatable Benefits for Those Who Love to Bet

by Scroll News
June 10, 2023
0

The well-known online betting platform FairPlay takes sports betting to new heights with the innovative Fantasy Pro....

FairPlay Offers Unbeatable Benefits for Betting Enthusiasts with Fantasy Pro

FairPlay Offers Unbeatable Benefits for Betting Enthusiasts with Fantasy Pro

June 10, 2023
The NeuroAid and Research Foundation supported by Apollo Hospitals is organising a Music therapy Event

The NeuroAid and Research Foundation supported by Apollo Hospitals is organising a Music therapy Event

June 9, 2023
Dr Vinod K Verma was Honored with Economic Times Inspiring Leaders Award 2023 for Remarkable Policy Advocacy Contributions

Dr Vinod K Verma was Honored with Economic Times Inspiring Leaders Award 2023 for Remarkable Policy Advocacy Contributions

June 8, 2023
Exciting times for Billiards & Snooker, as IOA authorizes participation of BSFI in the National Games: Rajan Khinvasara

Exciting times for Billiards & Snooker, as IOA authorizes participation of BSFI in the National Games: Rajan Khinvasara

June 8, 2023
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2022 Scroll News

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 Scroll News